Fun Health Facts

www.TrueHealthDC.com

November 6th, 2009 www.TrueHealthDC.com

Fact #1

A moody mineral with expanded benefits…

Lithium, most commonly and effectively used to treat depression and bipolar disorder, has also been shown to be effective in animal models of brain injury, stroke, Alzheimer’s, Huntington’s, Parkinson’s disease, amyotrophic lateral sclerosis (ALS), spinal cord injury, and other conditions.

Source: Review of Lithium Effects on Brain and Blood.


Fact #2

 

Thyroid-Liver connection.

Hypothyroidism can increase cholesterol, cause weight gain and may play a role in the development of nonalcoholic fatty liver which can progress to more severe liver disease.

According to new research, women who had a prior history of hypothyroidism for more than 10 years had a two to threefold higher risk of liver cancer compared to women without a history of thyroid disorders.

Source: Hypothyroidism In Women Associated With Liver Cancer


Fact #3

 

I entered a contest for the most prominent veins. I didn’t win but I came varicose.

Research has found that unstable carotid artery plaques, those in danger of rupturing and leading to a stroke, contain more inflammatory material and significantly less omega-3 fatty acids (you get these from non-farm raised fish, flax and other foods) than those with no symptoms or stable plaques.

This may imply that supplemental omega-3 fatty acid intake, such as that found in fish oil, may help prevent stroke.

Sources: Diminished omega-3 fatty acids are associated with carotid plaques from neurologically symptomatic patients: Implications for carotid interventions


Fact #4

 

Are you all getting the feeling that vitamin D is really, really, important.

Studies have demonstrated that an alarmingly large percentage of the elderly population show significant deficiencies in vitamin D.

Recently, a new study has shown that there is a direct relationship between those older adults with vitamin D inadequacies and an increased risk of dying from cardiovascular disease and all cause mortality.

Source: Prospective Study of Serum 25-Hydroxyvitamin D Level, Cardiovascular Disease Mortality, and All-Cause Mortality in Older U.S. Adults


Fact #5

 

New definition:
Flabbergasted, adj. Appalled by discovering how much weight one has gained.

Gastroesophageal reflux disease or GERD, otherwise known as indigestion, is typically treated with a class of drugs called proton pump inhibitors (PPI). These include such well known drugs as Prilosec, Prevacid, and Nexium.

A recent study revealed that patients on PPIs gained an average of 8 pounds over 2 years of use compared to those receiving a placebo.

Source: Long-term treatment with proton pump inhibitor is associated with undesired weight gain

Fact #1

A real pain in the nose, head…

A study that looked at the impact of sinus infections – also known as rhinosinusitis – found that women who seek treatment significantly outnumber men in all areas of the country.

Overall, about 14 percent of U.S. adults suffer from sinus infections each year, contributing to an estimated 91.2 million outpatient visits annually! The new study, supported by the U.S. National Institutes of Health, examined 4,617 visits to doctors’ offices and emergency departments in which patients sought treatment for the condition.

A combination of Oil of Oregano and Quercetin + Nettles may provide natural support for sinus problems without the side effects of prescription or OTC medications.

Oil of oregano has powerful anti-yeast, anti-bacterial, and anti-viral properties, as well as intestinal cleansing benefits. Quercetin is used for its anti-histamine and anti-inflammatory properties and nettle leaf for its anti-inflammatory support.


Fact #2

 

Ulcers are no fun at all.

An ulcer is a breakdown in the lining of the stomach or the first part of the small intestine. A certain type of bacterial infection is the most frequent cause, but lifestyle factors may also raise your risk.

The U.S. National Library of Medicine lists these preventive steps that may ward off a peptic ulcer:

  • Limit alcohol to no more than two drinks daily.
  • Stop smoking or chewing tobacco.
  • If you need to take painkillers, avoid anti-inflammatory drugs (NSAIDs) such as naproxen, ibuprofen or aspirin.

We use a blend of botanical extracts and nutrients with specific antimicrobial and mucosal healing properties. This novel combination of substances provides a new tool in management of ulcers and gastritis by addressing both the eradication of H. pylori and the healing of the mucosal tissue.


Fact #3

 

Besides bringing your sunscreen and beach ball to the beach, bring your selenium as well.

Higher blood levels of selenium may reduce the incidence of skin cancer by about 60 per cent, according to a new study.

The researchers report that the mineral was associated with reduced risks of both basal cell carcinoma (BCC) and squamous cell carcinoma (SCC).

The highest average selenium levels were associated with a 57 per cent reduction in the incidence of BCC, and a 64 per cent reduction in the incidence of SCC, compared to the lowest average selenium levels.

Relatively high serum selenium concentrations are associated with an approximately 60 per cent decrease in subsequent tumour incidence of both BCC and SCC0.


Fact #4

 

When your eyes are too big for your stomach, remember this.

A diet that includes key nutrients and low-glycemic index foods is likely to reduce risks for age-related macular degeneration (AMD), according to the results of a new study.

It was found that participants whose diets included higher levels of protective nutrients and of low-GI foods were at lowest risk for early and advanced AMD. A large body of science supports the role of lutein and other eye health ingredients such as zeaxanthin, vitamins C and E, and zinc, against the development of AMD.


Fact #5

 

Gamma tocopherol may be the belle of the vitamin E ball.

A gamma tocopherol rich mixture of mixed tocopherols inhibited colon cancer in mice. This may be due to the anti-inflammatory and anti-oxidative activities of tocopherols.

October 2nd, 2009

Fact #1

Magnesium, muscles and mortality.

A small segment of the population have genetic mutations that cause them to have very low levels of magnesium (Mg2+), which can cause altered heart beats, seizures, and involuntary muscle contraction.

In addition, it has been estimated that up to 60% of critically ill patients have low Mg2+ levels, and this is associated with increased mortality.

Source: A missense mutation in the Kv1.1 voltage-gated potassium channel–encoding gene KCNA1 is linked to human autosomal dominant hypomagnesemia


Fact #2

 

Olives aren’t just for martinis anymore.

Olive leaf extract, among its many antimicrobial properties, was recently shown to be effective against H. pylori and S. aureus including MRSA, in vitro.

Source: Antimicrobial activity of commercial Olea europaea (olive) leaf extract.


Fact #3

 

New definition:
Flabbergasted, adj. Appalled by discovering how much weight one has gained.

One of the many benefits of weight loss is in patients suffering with chronic kidney disease (CKD). Those that went on non-surgical weight loss regimes experienced decreases in proteinuria, blood pressure and decline in the disease process.

Source: Weight Loss Interventions in Chronic Kidney Disease: A Systematic Review and Meta-analysis


Fact #4

 

Boning up on green tea

Green tea polyphenols or more specifically the catechins demonstrated improvements in bone metabolism by promoting bone growth and decreasing bone reabsorption.

Source: Effects of Tea Catechins, Epigallocatechin, Gallocatechin, and Gallocatechin Gallate, on Bone Metabolism


Fact #5

 

If only those negative Vitamin E studies had told us this!

It has recently been reported that alpha-tocopherol (Vitamin E) has not delivered on its initial promise of improving cardiovascular health and reducing cancer risk. It appears one reason may be that supplementation with alpha-tocopherol alone may actually lower serum levels of gamma-tocopherol, which in many recent studies is showing to be the most active form in the Vitamin E family and was inversely associated with cardiovascular health and some cancers.

Source: Supplementation of Diets with Tocopherol Reduces Serum Concentrations of gamma and delta Tocopherol in Humans

September 18th, 2009

Fact #1

I’m all for going back to using smoke signals.

Past studies have determined that mobile phone use and the subsequent emission of low level EMR (electromagnetic radiation) can lead to oxidative damage in brain tissue. Ginkgo biloba has been shown to prevent mobile phone induced oxidative tissue damage.

Source: Ginkgo biloba prevents mobile phone-induced oxidative stress in rat brain.


Fact #2

Pretty in Pink

Astaxanthin, a carotenoid with powerful antioxidant properties and the pigment that gives salmon and krill its pinkish to dark red color, may protect against the development of diabetic kidney disease, says a new study.

Source: Protection against Oxidative Stress, Inflammation, and Apoptosis of High-Glucose-Exposed Proximal Tubular Epithelial Cells by Astaxanthin


Fact #3

A patient recovering from surgery was asked by a nurse how he was feeling.
“I’m OK but I didn’t like the four-letter-word the doctor used in surgery,” he answered.
“What did he say,” asked the nurse.
“OOPS!”

Patients receiving anesthesia prior to surgery may want to increase their intake of antioxidants as anesthesia may decrease levels of naturally occurring SOD and increase oxidative markers such as lipid peroxidation.

Source: Effect on free radical generation with different anesthesia.


Fact #4

Rats! I forgot to take my CLA today.

Rats fed a CLA (Conjugated Linoleic Acid) enriched diet were shown to exhibit increased concentrations of IgA and IgG immunoglobulins compared to rats feed a standard diet free of CLA.

Source: Higher immunoglobulin production in conjugated linoleic acid-supplemented rats during gestation and suckling


Fact #5

The pain of magnesium deficiency.

Substance P, a neuropeptide, has many functions including involvement in pain perception and the transmission of pain information to the central nervous system. Mice kept in a magnesium deficient state demonstrated increased levels of Sunstance P and inflammatory markers including cytokines, including interleukin-1, interleukin-6, and tumor necrosis factor.

Source: Scientific Evidence for Musculoskeletal, Bariatric, and Sports Nutrition, (Ingrid Kohlstadt MD MPH FACN editor) CRC Press 2006.

Friday August 28th, 2009

Fact #1

The way to the eyes may be through the stomach.

Age-related Macular Degeneration (AMD), the leading cause of blindness in the UK, could be reduced by up to 20% by increasing the amount of fruit, vegetables and nuts in the diet.

Says Professor Ian Grierson, “…if we can improve the kind of food that we eat, we could dramatically reduce the number of people who may suffer from eye diseases in the future.” ~ Really, just eye diseases? He must be a ophthalmologist. Wonder what a cardiologist, or a neurologist, or an internist say…if they had the slightest clue of nutritional medicine. They are WAY behind the times. I think I speak from all of us Functional Medicine doctors, when I say, “Fact number 1 get a…duh!”


Fact #2

What did the farmer call the cow that would not give him any milk? An udder failure!

Bovine colostrum has been shown to possess antibacterial and immune modulating properties. Studies have shown bovine colostrum to decrease inflammatory markers such as IL-6 and CRP as well. Also, colostrum has the ability to neutralize lipopolysaccharides arising from gram negative bacterial pathogens.


Fact #3

There’s nothing sinful about synbiotics and synergy.

A combination of probiotic and prebiotics may improve the quality of life for sufferers of ulcerative colitis, says a new study.

Consumption of both the probiotic Bifidobacterium longum and prebiotic psyllium led to improvements in the quality of life of people suffering from ulcerative colitis.

Researchers report that individual supplementation with the probiotic or the prebiotic did not produce statistically significant improvements in the quality of life, and that only the synbiotic approach was effective.


Fact #4

You can actually C the improvement!
Increased intake of vitamin C-rich foods may reduce the risk of hardening of the arteries, and ultimately protect against heart disease, says a new study.

“Increased intake of vitamin C and fruit and berries seemed to contribute to the lesser progression of the carotid intima media thickness in elderly men who were given dietary advice,” wrote lead author Ingrid Ellingsen.


Fact#5

“Can I take this in the form of blueberry pie ala mode?”

Extracts from blueberries may reduce the size of tumors primarily found in infants and children, and improve survival, suggest new findings from a study with mice.

According to new results from the Ohio State University, mice fed the blueberry extract doubled their lifespan, and had tumors 60 per cent smaller than in control mice.

“This work provides the first evidence demonstrating that blueberry extract can limit tumor formation by inhibiting the formation of blood vessels and inhibiting certain signaling pathways,” said lead author Gayle Gordillo.

“Oral administration of blueberry extract represents a potential therapeutic strategy [against] endothelial cell tumors in children.”

Friday August 7th, 2009

Fact #1

The better zinc.

A recent study has revealed that a unique form of zinc, zinc bis-glycinate, demonstrated significantly increased oral bioavailability of zinc compared with the more commonly used zinc gluconate form.

Source: A Bioavailability Study Comparing Two Oral Formulations Containing Zinc (Zn Bis-Glycinate vs. Zn Gluconate) After a Single Administration to Twelve Healthy Female Volunteers


Fact #2

I won’t stop raving about vitamin D until I stop seeing studies like these.

It appears that the lower a person’s level of serum Vitamin D is, the higher the prevalence of developing metabolic syndrome, according to a new study.

The authors theorize that in overweight and obese individuals, the fat soluble vitamin may be sequestered in adipose tissue thereby decreasing its availability in circulating blood.

Coincidentally, in a separate study, children with the lowest vitamin D levels were more likely to have higher blood pressure, high blood sugar levels and low blood levels of HDL cholesterol, than those children with the highest levels of the vitamin.

Source: Serum 25-hydroxyvitamin D is independently associated with high-density lipoprotein cholesterol and the metabolic syndrome in men and women


Fact #3

Q: What do you have when the Spice girls are buried up to their necks in sand?
A: Not enough sand.

Post menopausal women who have received a combination of estrogen and progestin hormone replacement therapy increase their risk of developing progestin-accelerated breast tumors in the future. In past studies, it’s been shown that progestin increases the development of certain tumors by increasing production of VEGF, a molecule that helps supply blood to the tumor.

In a recent study though, curcumin, a group of polyphenolic plant pigments which is responsible for the spice turmeric’s characteristic golden yellow color, demonstrated an ability to inhibit progestin-induced VEGF secretion from breast cancer cells.

Source: Curcumin delays development of medroxyprogesterone acetate-accelerated 7,12-dimethylbenz[a]anthracene-induced mammary tumors.


Fact #4

I believe Count Chocula is very envious of Frankenberry right about now.

Supplementation of berry derived anthocyanidins, a type of polyphenol and flavonoid, was shown to significantly modulate both HDL and LDL types of cholesterol in a recent study.

Source: Anthocyanin supplementation improves serum LDL- and HDL-cholesterol concentrations associated with the inhibition of cholesteryl ester transfer protein in dyslipidemic subjects


Fact #5

Are you getting a feeling that we all need to increase our polyphenol intake?

Individuals who drink five or more cups of green tea per day may reduce the risk of blood- and lymph-based cancers by about 50 per cent, says a new study.

What was impressive was that compared to people who drank only one cup per day, five cups of green tea a day were associated with a 42 per cent reduction in hematologic malignancies, and a 48 per cent risk reduction in lymphoid neoplasms, according to findings. Epigallocatechin gallate, known as EGCg, has recently been discovered as the active ingredient in green tea, giving it its antioxidant and DNA protective abilities.

Source: Green Tea Consumption and Hematologic Malignancies in Japan

Friday July 10th, 2009  www.TrueHealthDC.com

Fact #1

Save your figure.

According to a new study conjugated linoleic acid (CLA) supplementation reduced total body fat and lowered the body mass index (BMI), a common health measure of weight relative to height, in obese postmenopausal women with Type 2 diabetes. CLA appears to allow the body to burn calories in a heat-producing way, says one of the researchers.

Source: Comparison of dietary conjugated linoleic acid with safflower oil on body composition in obese postmenopausal women with type 2 diabetes mellitus


Fact #2

Stress is when you wake up screaming and you realize you weren’t asleep.

Researchers found that the pattern of gene expression differed between caregivers of family members with cancer relative to a matched group of individuals who did not have this type of life stress. They found that among the caregivers, even though they had normal cortisol levels in their blood, the pattern of gene expression in the monocytes was altered so that they were relatively less responsive to the anti-inflammatory actions of cortisol, but relatively more responsive to pro-inflammatory actions of NF-κB.

“In other words,” according to the researchers, “something goes awry in caregivers’ white blood cells so they are not able to ‘receive’ the signal from cortisol that tells them to shut down inflammation.”

These findings might help to explain why the caregivers would seem to be in a chronic pro-inflammatory state, a condition of immunologic activation. This activated state could contribute to the risk for a number of medical illnesses, such as depression, heart disease, and diabetes.

Source: A Functional Genomic Fingerprint of Chronic Stress in Humans: Blunted Glucocorticoid and Increased NF-κB Signaling


Fact #3

Save your hair.

People with trichotillomania, a disorder characterized by compulsive hair-pulling were enrolled in a study in which they were given N-Acetyl Cysteine. After nine weeks, those on the supplement had significantly reduced hair-pulling. By the end of the 12 week study, 56 percent reported feeling much or very much improved, while only 16 percent on the placebo reported less pulling.

This supplement seems to restore the extracellular glutamate concentration in the nucleus accumbens making it easier for patients to decrease this behavior.

Source: N-Acetylcysteine, a Glutamate Modulator, in the Treatment of Trichotillomania


Fact #4

Save your brain.

According to a new hypothesis, low blood levels of vitamin D may increase the risk of dementia and Alzheimer’s disease.

A growing number of studies have linked deficiency of vitamin D to increased risks of cardiovascular diseases, diabetes, osteoporosis, depression, and periodontal disease, all of which have been linked to some degree to increased risks for dementia.

Based on these risk factors, William Grant, PhD, from the Sunlight, Nutrition, and Health Research Center hypothesizes that vitamin D deficiency may also be a risk factor for dementia.

In a separate study, increased intake of fish may reduce the risk of dementia by about 20 per cent.

“Our results extend findings on the associations of fish and meat consumption with dementia risk to populations in low- and middle-income countries and are consistent with mechanistic data on the neuroprotective actions of omega-3 long-chain polyunsaturated fatty acids commonly found in fish,” said the researchers.

Source: Dietary fish and meat intake and dementia in Latin America, China, and India: a 10/66 Dementia Research Group population-based study


Fact#5

“Walk this way!”

Senior citizens who consume a high dietary intake of carotenoids are able to walk ‘longer and stronger’ than those with a low dietary intake, suggest the results of a new study.

Results showed that a higher dietary intake of fruits and vegetables, as indicated by a higher blood carotenoid level, was associated with a significant protective effect against physical degeneration over the course of three years, as measured by a strong or weak walking performance.

Source: Low serum carotenoids are associated with a decline in walking speed in older women

Friday June 26th, 2009  www.TrueHealthDC.com

Fact #1

If you’re having a difficult time quitting smoking make sure to use this powerful antioxidant.

People with chronic obstructive pulmonary disease (COPD) could one day benefit from an antioxidant compound in broccoli, researchers report.

“In COPD, there is critical loss of antioxidant systems, which protect against oxidative stress and inflammation,” explained lead researcher Shyam Biswal, an associate professor in the department of environmental health sciences and the division of pulmonary and critical care medicine at Johns Hopkins School of Medicine, in Baltimore.

“Even though there is a loss of this system, you can substantially restore it with an activator for this pathway,” Biswal said. A compound in broccoli called sulforaphane has been shown effective in restoring antioxidant gene activity. “So this could be a new way of doing therapy,” Biswal theorized.


Fact #2

This yeast hurts the least.

In a recent study, red yeast rice supplements, when combined with diet and lifestyle changes, were found to lower LDL, or bad cholesterol, levels by more than 20 percent without a substantial risk of muscle pain or myalgia, the most common side effect associated with prescription statin use.

Click here to view an ABC News video on this very topic


Fact #3

Here’s the SKINny on vitamin D.

Oral supplements of vitamin D may boost production of protective compounds in the skin, and may ultimate help prevent skin infections, according to a new study.

The small study focused on patients with atopic dermatitis, characterised by areas of severe itching, redness and scaling, and found that supplements of vitamin D enhanced the skin’s ability to produce a peptide called cathelicidin, which protects against microbial invasion.

Gallo and his co-workers recruited 14 people with moderate to severe atopic dermatitis and 14 people with normal skin. All of the participants were given daily vitamin D supplements of 4000 IUs for 21 days.


Fact #4

It appears a good needling in this case is a good thing.

A review of seven clinical trials of acupuncture given with embryo transfer in women undergoing in vitro fertilization (IVF) suggests that acupuncture may improve rates of pregnancy. The reviewers found that acupuncture given as a complement to IVF increased the odds of achieving pregnancy. According to the researchers, the results indicate that 10 women undergoing IVF would need to be treated with acupuncture to bring about one additional pregnancy.


Fact#5

This certainly isn’t a bone of contention.

Researchers found that using a fumarate version of L-carnitine stimulated bone formation, improving bone density, bone size and bone microarchitecture.

Friday June 19th, 2009

Fact #1

This yeast hurts the least.

In a recent study, red yeast rice supplements, when combined with diet and lifestyle changes, were found to lower LDL, or bad cholesterol, levels by more than 20 percent without a substantial risk of muscle pain or myalgia, the most common side effect associated with prescription statin use.

Source: Red Yeast Rice for Dyslipidemia in Statin-Intolerant Patients

Click here to view an ABC News video on the same topic


Fact #2

D stands for diet.

According to a new study, the addition of vitamin D to a reduced-calorie diet may lead to better weight loss.

To learn more about healthy weight loss, click here to listen to Wednesday’s Clinical Rounds discussion with Jerry Bailey, BAA, CD, FIAMA.

Source: Successful Weight Loss With Dieting Is Linked To Vitamin D Levels


Fact #3

B all you can B.

Chemotherapy can often cause long term development of leukemias. Niacin supplementation of cancer patients may decrease the severity of short- and long-term side effects of chemotherapy, and could improve tumor cell killing through activation of poly(ADP-ribose)-dependent apoptosis pathways.

Source: Niacin status and treatment-related leukemogenesis


Fact #4

It’s CoQ10…again

Supplements of co-enzyme Q10 may improve the motility and density of sperm in infertile men, according to a new study.

The researchers reported a significant improvement in both sperm density and motility following supplements of the coenzyme. A positive association was also found with regards to sperm count. Further analysis showed an increase in the percent of normal forms of sperm.

Source: Q10 on Semen Parameters, Sperm Function and Reproductive Hormones in Infertile Men


Fact#5

Take Glutathione Power™ after eating your swordfish.

Glutathione peroxidase, an enzyme family with peroxidase activity whose main role is to protect cells from oxidative damage, completely blocked Methylmercury induced mitochondrial lipid peroxidation. Cells treated with methylmercury showed a significant reduction in glutathione peroxidase activity. Also, there was a significant decrease in cell viability and an increase in apoptosis.

A recent study suggests that glutathione peroxidase is an important target for methylmercury -induced neurotoxicity, presumably because this enzyme is essential for counteracting the pro-oxidative effects of methylmercury both in vitro and in vivo.

Source: Methylmercury neurotoxicity is associated with inhibition of the antioxidant enzyme glutathione peroxidase

Friday May 29th, 2009

Fact #1

Gamma tocopherol may be the belle of the vitamin E ball.

A gamma tocopherol rich mixture of mixed tocopherols inhibited colon cancer in mice. The inhibition may be due to the apoptosis-inducing, anti-inflammatory, antioxidative, and reactive nitrogen species-trapping activities of tocopherols.

Source: A gamma-tocopherol-rich mixture of tocopherols inhibits colon inflammation and carcinogenesis in azoxymethane and dextran sulfate sodium-treated mice.

Fact #2

And yet another vitamin takes on colon cancer.

Increased intake of vitamin B6 from dietary and supplements may reduce the risk of colorectal cancer by over 50 per cent, suggests a new study.

Researchers report that PLP levels were positively correlated with blood levels of folate and vitamin B12. PLP levels were also slightly inversely correlated blood levels of homocysteine, and the inflammatory markers C-reactive protein (CRP), tumor necrosis factor-alpha receptor 2, and interleukin-6 (IL-6).

Regarding the incidence of colorectal cancer, plasma PLP levels were inversely linked with risk of colorectal cancer, said the researchers. Indeed, when increasing levels were found to decrease the risk by 8, 58, and 51 per cent, they said.

Source: Prospective Study of Plasma Vitamin B6 and Risk of Colorectal Cancer in Men

Fact #3

Maybe my colon simply needs a nap.

Serotonin is best known as a chemical in the brain that plays an important role as a neurotransmitter in the modulation of anger, aggression, body temperature, mood, sleep, human sexuality, appetite, and metabolism. Did you know though, that approximately 95% of serotonin is located in the cells of the gut wall, where it regulates contraction, the movement of the bowel, and the secretion of fluid in the bowel?

One theory as to why some people have IBS (Irritable Bowel Syndrome) may have to do with this neurotransmitter. When there’s an abnormal amount of serotonin in the gut, or if there’s an abnormality in the function of serotonin, it can lead to abdominal pain, cramping, and changes in bowel habits, especially loose stools.

Source: Role of serotonin in the pathophysiology of the irritable bowel syndrome

Fact #4

When your eyes are too big for your stomach, remember this.

When your eyes are too big for your stomach, remember this. A diet that includes key nutrients and low-glycemic index foods is likely to reduce risks for age-related macular degeneration (AMD), according to the results of a new study.

The new research found that participants whose diets included higher levels of protective nutrients and of low-GI foods were at lowest risk for early and advanced AMD.

A large body of science supports the role of lutein and other eye health ingredients such as zeaxanthin, vitamins C and E, and zinc, against the development of AMD.

Source: Dietary Compound Score and Risk of Age-Related Macular Degeneration in the Age-Related Eye Disease Study

Fact #5

Besides bringing your sunscreen and beach ball to the beach, bring your selenium as well.

Higher blood levels of selenium may reduce the incidence of skin cancer by about 60 per cent, according to a new study.

The researchers report that the mineral was associated with reduced risks of both basal cell carcinoma (BCC) and squamous cell carcinoma (SCC).

The highest average selenium levels of between 1.3 and 2.8 micromoles per litre were associated with a 57 per cent reduction in the incidence of BCC, and a 64 per cent reduction in the incidence of SCC, compared to the lowest average selenium levels of between 0.4 and 1.0 micromoles per litre.

“Relatively high serum selenium concentrations are associated with an approximately 60 per cent decrease in subsequent tumour incidence of both BCC and SCC,” wrote the researchers, “where as serum concentrations of carotenoids or alpha-tocopherol are not associated with later skin cancer incidence.”

Source: Serum Antioxidants and Skin Cancer Risk: An 8-Year Community-Based Follow-up Study

Friday May 22, 2009

Fact #1

This root may get to the root of the problem.

Curcumin, the major polyphenol found in turmeric, appears to reduce weight gain and suppress the growth of fat tissue in mice and cell models.

“Weight gain is the result of the growth and expansion of fat tissue, which cannot happen unless new blood vessels form, a process known as angiogenesis.” said senior author Mohsen Meydani, DVM, PhD, director of the Vascular Biology Laboratory at the USDA HNRCA. “Based on our data, curcumin appears to suppress angiogenic activity in the fat tissue of mice fed high fat diets.”

Source: Curcumin Inhibits Adipogenesis in 3T3-L1 Adipocytes and Angiogenesis and Obesity in C57/BL

Fact #2

Magnesium is magnificent for high blood pressure.

Supplemental magnesium may reduce blood pressure in people with high blood pressure, but with seemingly normal magnesium levels, says a new study. On the other hand, the supplements had no effect on the blood pressure measurements of normo-tensive individuals, according to findings. “These findings suggest that magnesium supplementation may help prevent the progression of hypertension in normo-magnesemic non-diabetic overweight people with higher BP, although mechanisms of counter-regulation preventing further BP increase remain to be elucidated,” wrote the researchers.

Source: Effects of oral magnesium supplementation on insulin sensitivity and blood pressure in normo-magnesemic nondiabetic overweight Korean adults.

Fact #3

This may make pork chops out of the swine flu.

There is compelling epidemiological evidence that indicates that because of vitamin D’s seasonal and population effects on innate immunity, vitamin D deficiency may explain influenza’s seasonality.

In 1992, Hope-Simpson predicted that, “understanding the mechanism (of the seasonal stimulus) may be of critical value in designing prophylaxis against the disease.” Twenty-five years later, Aloia and Li-Ng found 2,000 IU of vitamin D per day abolished the seasonality of influenza and dramatically reduced its self-reported incidence.

Source: On the epidemiology of influenza

Fact #4

Again, exercise to the rescue.

A home-based diet and exercise program reduced the rate of functional decline among older, overweight long-term survivors of colorectal, breast and prostate cancer, according to a new study.

“In conclusion, this study provides data on a long overlooked, yet important faction in older long-term cancer survivors. Long-term survivors of colorectal, breast, and prostate cancer participating in a diet and exercise intervention reduced the rate of self-reported physical function decline in comparison with a group receiving no intervention,” the researchers write.

Source: Effects of Home-Based Diet and Exercise on Functional Outcomes Among Older, Overweight Long-term Cancer Survivors

Fact #5

Gee, I thought I only had to worry about my car emissions.

Fish oil can affect the methane-producing bacteria in the rumen, a part of the cow’s gut leading to reduced emissions.

“The fish oil affects the methane-producing bacteria in the rumen part of the cow’s gut, leading to reduced emissions. Understanding which microbial species are particularly influenced by changes in diet and relating them to methane production could bring about a more targeted approach to reducing methane emissions in animals.”

Source: Fish Oils Reduce Greenhouse Gas Emissions From Flatulent Cows

Friday May 15th, 2008

Fact #1

““Ladies and Gentlemen, let’s get ready to rumble! In the red corner is the undisputed heavy weight champion of the lipid balancing world, let’s hear it for Designs for Health’s Lipotrienols RYR™.”

Red yeast rice, given to test subjects over an 8 week period, demonstrated a significant impact on modulating blood serum lipids.

Lipotrienols RYR™ is a powerful combination of natural substances intended to support normal blood lipid levels and optimize cardiac and vascular health. The red yeast rice in Lipotrienols RYR™is USDA certified organic and grown in the USA. Designs for Health takes great care to assay our red yeast rice to assure that there are undetectable levels of citrinin (< 1 ppm).

Source: Efficacy of Monascus purpureus Went rice on lowering lipid ratios in hypercholesterolemic patients.

Fact #2

You can’t pick a bone with DHEA.

Taking a DHEA supplement combined with vitamin D and calcium can significantly improve spinal bone density in older women, according to a new study.

“The results of our study are very promising. Similar studies have demonstrated much smaller benefits for bone than we found. However, calcium and vitamin D deficiencies, which are present in half of older adults, may have prevented DHEA from improving bone density in the earlier studies,” said Edward Weiss, Ph.D., associate professor of nutrition and dietetics at Saint Louis University’s Doisy College of Health Sciences and lead author of the study.

Low DHEA concentration has been associated with low bone density, which led researchers to question whether restoring DHEA levels could improve or preserve bone health.

Source: Dehydroepiandrosterone replacement therapy in older adults: 1- and 2-y effects on bone1,2,3

Fact #3

If only those negative alpha-tocopherol studies had told us this!

If only those negative alpha-tocopherol studies had told us this!
It has recently been reported that alpha-tocopherol has not delivered on its initial promise of improving cardiovascular health and reducing cancer risk. It appears one reason may be that supplementation with alpha-tocopherol alone may actually lower serum levels of gamma-tocopherol, which in many recent studies is showing to be the most active form in the tocopherol family and was inversely associated with cardiovascular health and some cancers.

Source: Supplementation of Diets with Tocopherol Reduces Serum Concentrations of gamma and delta Tocopherol in Humans

Fact #4

A guy walks past a mental hospital and hears a moaning voice ” … 13 … 13 … 13 … “.

The man looks over to the hospital and sees a hole in the wall. He looks through the hole and gets poked in the eye. The moaning voice then groaned ” … 14 … 14 … 14 … “.

Researchers have discovered that a form of vitamin B1 could become a new and effective treatment for one of the world’s leading causes of blindness.

Scientists believe that uveitis, an inflammation of the tissue located just below the outer surface of the eyeball, produces 10 to 15 percent of all cases of blindness in the United States, and causes even higher rates of blindness globally. The inflammation is normally treated with antibiotics or steroid eye drops.

“Benfotiamene strongly suppresses this eye-damaging condition and the biochemical markers we associate with it,” said UTMB associate professor Kota V. Ramana, senior author of the study. “We’re optimistic that this simple supplementation with vitamin B1 has great potential as a new therapy for this widespread eye disease.”

Source: Prevention of Endotoxin-Induced Uveitis in Rats by Benfotiamine, a Lipophilic Analogue of Vitamin B1

Fact #5

He said, he said.

In more health related news, it has recently been reported that supplements of antioxidant vitamins after exercise may decrease the benefits of the workout by blocking the positive effects of reactive oxygen species. Researchers have reported that antioxidant vitamins C and E may blunt the positive effects of exercise, with respect to insulin sensitivity.

Reacting to the study, Alexander Schauss, PhD, from AIBMR Life Sciences, said, “The primary objective of this study was to study the effect of a 4-week intensive 5-days a week exercise program on insulin sensitivity. Yet the title of the paper leads one to believe otherwise,” he said.

“This is a small gender-biased study of 40 male subjects, 25 to 35 years of age. When I read through the study for the first time I had to wonder how could the authors have come up with such a title for their paper?”, he asked.

Dr. Schauss goes on to say, “Skeletal muscle biopsies were obtained from the right vastus lateralis muscle of study subjects. But some of the data is missing for a number of subjects, and reported as such by the authors,” said Dr Schauss.

The authors noted that biopsies for the ‘early’ time-point were only obtained from five people in the vitamin group, and four in the placebo group. “Yet the authors conclude a “strong induction of PGCl-alpha, PGCl-beta, and PPAR-gamma expression in skeletal muscle following 4 weeks of exercise training in previously untrained, antioxidant naïve individuals” and “markedly reduced exercise-related induction” in those taking antioxidants, based on these limited number of biopsies,” said Dr Schauss.

“Would it not have made more sense to appropriately increase the intensity and duration of exercise slowly and then see if the subject’s bodies didn’t accommodate handling of ROS without a significant change in induction of these markers?” he said.

Source: Antioxidants prevent health-promoting effects of physical exercise in humans

Friday April 10th, 2009 www.TrueHealthDC.com

Fact #1

I guess this means easy on the cannoli.

According to a recent study, a Mediterranean diet may significantly decrease the risk of Alzheimer’s disease and other forms of dementia.

“We know from previous research that a healthy diet like this is protective for cardiovascular risk factors like cholesterol, hypertension and diabetes,” said researcher Nikolaos Scarmeas. “Now this current study shows it may help brain function too.”

The Mediterranean diet refers to a diet high in vegetables, legumes, fish and monounsaturated fat sources such as olive oil, and low in saturated fats, meat and dairy. Researchers noted that the traditional diet of parts of Greece and Italy was as high in fat as the U.S. diet, but rates of heart disease were much lower.

Source: Mediterranean Diet and Mild Cognitive Impairment
Fact #2

…and it doesn’t deplete CoQ10 levels.

Lab animals supplemented with lipoic acid experienced lowered triglyceride levels up to 60 percent.

“The extent of triglyceride reduction was really dramatic, we didn’t expect it to be this profound,” said Regis Moreau, an assistant professor with the Linus Pauling Institute at Oregon State University. “The potential is good that this could become another way to lower blood triglycerides and help reduce the risk of atherosclerosis. It’s pretty exciting.”

Research suggests that Lipoic Acid increases the need for Biotin by lowering levels of Biotin dependent enzymes. Thus Lipoic Acid should always be taken with biotin.

Source: Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and downregulating liver triacylglycerol secretion.

Fact #3

“Beam me up, Scotty.”

Physical medicine practitioners have found a useful technology which can speed up and promote muscular and tendonous healing. Low level laser therapy has been shown to improve collagen fiber organization, increase mitochondrial activity in muscular fibers, activate fibroblasts and macrophages and stimulate angiogenesis.

Source: Ultrastructural analysis of the low level laser therapy effects on the lesioned anterior tibial muscle in the Gerbil.
Fact #4

Broccoli soup anyone?*

Daily consumption of broccoli sprouts may cut Helicobacter pylori infections, and offer protection against stomach ulcers, and maybe cancer, says a new study.

Japanese men and women with H. pylori infections who consumed 70 grams a day of fresh broccoli sprouts had lower levels of the bacteria after eight weeks than men and women consuming alfalfa sprouts, according to the study.

Cruciferous vegetables contain high levels of the active plant chemicals glucosinolates. These are metabolised by the body into isothiocyanates, which are known to be powerful anti-carcinogens. The main isothiocyanate from broccoli is sulphoraphane.

Source: Dietary Sulforaphane-Rich Broccoli Sprouts Reduce Colonization and Attenuate Gastritis in Helicobacter pylori–Infected Mice and Humans
Fact #5

Docosahexanoic acid (DHA) in Fish oils may fight cancer.

Docosahexanoic acid (DHA), an omega-3 fatty acid found in fish oils, has been shown to reduce the size of tumors and enhance the positive effects of the chemotherapy drug cisplatin, while limiting its harmful side effects.
The researchers found that, at the molecular level, DHA acts by reducing leukocytosis (white blood cell accumulation), systemic inflammation, and oxidative stress, all processes that have been linked with tumor growth.

Source: Chemopreventive and renal protective effects for docosahexaenoic acid (DHA): implications of CRP and lipid peroxides

Friday March 27th, 2009  www.TrueHealthDC.com

Fact #1

Nancy Reagan could have just as easily said, “Just say no to fructose”.
Glucose and fructose act quite differently in the brain, primarily in the hypothalamus. Glucose will decrease food intake and fructose, conversely, will increase food intake. Both of these sugars signal in the brain through the malonyl-CoA signaling pathway and have inverse effects on food intake.

Researcher M. Daniel Lane commented, “We feel that these findings may have particular relevance to the massive increase in the use of high fructose sweeteners (both high fructose corn syrup and table sugar) in virtually all sweetened foods, most notably soft drinks. The per capita consumption of these sweeteners in the USA is about 145 lbs/year and is probably much higher in teenagers/youth that have a high level of consumption of soft drinks. There is a large literature now that correlates, but does not prove that a culprit in the rise of teenage obesity may be fructose.”

Source: Effect of glucose and fructose on food intake via malonyl-CoA signaling in the brain.
Fact #2

Unfortunately, in this case, heavy metal doesn’t refer to loud guitars and tight spandex.
At a recent conference, Dr. Neil Ward, professor of chemistry at the UK’s University of Surrey, who has studied the relation of trace elements to human disorders for over 25 years, briefly discussed how some trace elements can contribute to aggressive or anti-social behaviour.

These elements can impede the absorption of certain beneficial minerals and vitamins leading to nutrient depletion which has been linked to anti-social behaviour. For example, “Lead acts as an anti-nutrient, hindering the utilisation of magnesium, zinc and vitamin B1. High lead levels have been linked to a reduction in IQ, negative classroom behaviour ratings by teachers, juvenile delinquency and increased violent behaviour,” he said.

Source: How metals in food impact children’s behaviour.
Fact #3

Too bad the researchers didn’t also give vitamin K a look for a decrease in heart attacks.
Older adults given bread supplemented with 5000 IU of vitamin D per daily serving, demonstrated significant increases in bone mineral density without evident adverse effects.

Source: Long-term effects of giving nursing home residents bread fortified with 125 microg (5000 IU) vitamin D(3) per daily serving.
Fact #4

Taurine helps bull over alcohol induced liver injury.
Taurine, when used in rat models, prevented alcohol induced oxidative stress and attenuated liver injury.

Also, adiponectin, a protein hormone that modulates a number of metabolic processes, including glucose regulation and fatty acid catabolism, which has been shown to prevent liver injury in mice, can be decreased with ethanol consumption. Taurine normalized adiponectin messenger RNA regulation and serum adiponectin concentrations.

Source: Taurine supplementation prevents ethanol-induced decrease in serum adiponectin and reduces hepatic steatosis in rats.
Fact #5

Do they still make those black licorice whips we used to eat when we were kids?
As research continues in the study of cancer, it is becoming more evident that inflammation is a key component in cancer’s initial formation and subsequent proliferation.

In a recent study, researchers demonstrated that inhibiting the enzyme 11β-hydroxysteroid dehydrogenase type 2 (11βHSD2), by treatment with glycyrrhizic acid, a natural compound found in licorice, prevents colorectal cancer progression in mice predisposed to the disease.

The researchers examined expression of 11βHSD2 in human colon polyps and in the colons of mice predisposed to colon cancer. They found that 11βHSD2 was increased in polyps found in both mice and humans and correlated with COX-2 expression and activity.

Source: Inhibition of 11β–hydroxysteroid dehydrogenase type II selectively blocks the tumor COX-2 pathway and suppresses colon carcinogenesis in mice and humans.

Friday March 20th, 2009 www.TrueHealthDC.com
Fact #1

Krill Oil may Help Reduce Inflammation in Cardiovascular Disease (CVD).
As oxidative stress and inflammation are associated with an increase in cardiovascular disease risk, astaxanthin, an oxygenated carotenoid found in Krill Oil, was found to address both of these aspects of cardiovascular health in a recent study.

Dark Red Krill Oil contains exceptionally high levels of both esterfied astaxanthin and phospholipids, and is made using a unique cold-extraction process that converts it into stable oil. This process protects the lipids from alteration and avoids peroxidation.

Source: Astaxanthin: a novel potential treatment for oxidative stress and inflammation in cardiovascular disease.

Fact #2

“Can you see the real me, doctor, doctor!”*

Supplements of lutein, long-reported to have benefits for eye health, may protect against the detrimental effects of long-term computer display light exposure, say’s a new study.

“Visual function in healthy subjects who received the lutein supplement improved, especially in contrast sensitivity, suggesting that a higher intake of lutein may have beneficial effects on the visual performance,” wrote the researchers.

Source: A 12-week lutein supplementation improves visual function in Chinese people with long-term computer display light exposure

Fact #3

Milk thistle has always been one of my favorite herbs.

Not only does milk thistle demonstrate hepatoprotective properties but also anticarcenogenic properties as well. In addition, milk thistle’s iron-chelating effect is one mechanism by which it might benefit people with the Hepatitis C virus, as high iron levels are associated with advanced fibrosis and increased risk of hepatic cancer in people with HCV.

Source: Silybin treatment is associated with reduction in serum ferritin in patients with chronic hepatitis C.

Fact #4

People who have had heart attacks are likely to have been in traffic right before their symptoms started, according to new research.

“Driving or riding in heavy traffic poses an additional risk of eliciting a heart attack in persons already at elevated risk,” said Annette Peters, Ph.D., lead author of the study and head of the research unit at the Institute of Epidemiology, Helmholtz Zentrum Muchen, Germany. “In this study, underlying vulnerable coronary artery disease increased the risk of having a heart attack after driving in traffic.”

Fact #5

Adolescents with high intakes of vitamin D may have lower overall body fat and lower amounts of abdominal fat, says a new study.

The results have particular importance since abdominal fat, also known as visceral fat, has been linked to a range of health risks such as heart disease, stroke, diabetes and hypertension.

Source: Low Vitamin D Levels Associated With Several Risk Factors In Teenagers

Friday March 13th, 2009  www.TrueHealthDC.com

Fact #1

My mother started walking five miles a day when she was 60. She’s 97 now and we have no idea where she is.
A meta-analysis of 28 studies of cancer related fatigue found that exercise is more effective at combating fatigue than the usual care provided to patients.

“I believe, in the future, exercise in oncology can play a role, as much a role as exercise plays in cardiac rehab, but we need to do the types of large trials, appropriately powered to answer these questions,” said Karen Mustian, an assistant professor in the Department of Radiation Oncology at the University of Rochester School of Medicine, who was not involved with the review.

Source: Exercise for the management of cancer-related fatigue in adults.

Fact #2

Folic acid may decrease risk of prostate cancer.
A study found that men who took a daily folic acid supplement of 1 mg daily had more than twice the risk of prostate cancer compared with men who took a placebo.

“The synthetic form of folate, folic acid, found in supplements, is more bioavailable compared to folate from dietary sources and we know the amount of folate available is critical,” says lead author Jane Figueiredo, Ph.D., assistant professor of preventive medicine at the Keck School of Medicine of USC. “Adequate levels of folate may be beneficial, but too much folate is unlikely to be beneficial.” “These findings highlight the potentially complex role of folate in prostate cancer. The possibility of different effects from folic acid-containing supplements versus natural sources of folate definitely merits further investigation.”

Source: Folic Acid and Risk of Prostate Cancer: Results From a Randomized Clinical Trial.
Fact #3

“This gout has got my ankle swollen bigger than Madonna’s ego.”
Higher intakes of vitamin C may reduce a man’s risk of gout, the most prevalent inflammatory arthritis in adult males, by up to 45 per cent, says a new study. According to the research findings, for every 500 milligrams increase in vitamin C intake, a man’s risk of gout was cut by 17 per cent. And for men with vitamin C intakes of at least 1,500 milligrams per day, the risk of gout was cut by 45 per cent.

Source: Vitamin C intake and the risk of gout in men: a prospective study.
Fact #4

Green tea chewing gum anyone? Hey, maybe the double mint twins need a job.
Consuming green tea may offer protection against gum disease, a condition that may affect over 30 per cent of the population, suggests a new study. The researchers propose that catechins, the polyphenols found in green tea, may interfere with the body’s inflammatory response to periodontal bacteria, thereby promoting periodontal health, and warding off further disease.

Source: Relationship between intake of green tea and periodontal disease.
Fact #5

Another case of iffy science?
Jack Chellam, a regular contributor to the journal Alternative and Complementary Therapies, points out two main problems with a study published in the journal Cancer Research which concluded that vitamin C given to mice or cultured cells treated with common anti-cancer drugs reduces the antitumor effects of the chemotherapeutic agents.

Challem points out two main problems with the study: the oxidized form of vitamin C (dehydroascorbic acid) and not actual vitamin C (ascorbic acid) was used and in the mouse experiments, the animals were given toxic doses of dehydroascorbic acid, a compound that is not used as a dietary supplement in humans.

“This study and the subsequent headlines [it generated] were a grievous disservice to physicians and patients with cancer,” says Challem. He adds that “considerable positive research…has shown striking benefits from high-dose vitamin C (ascorbic acid) in cancer cells and animals—and in actual human beings.”

Source: Should Vitamin C Be Used as an Adjunctive Treatment in Cancer?

Friday March 6th, 2009 www.TrueHealthDC.com

Fact #1

B aggressive with homocysteine and celiac disease.

Daily supplements of B vitamins may improve the overall health of people with celiac disease by reducing levels of homocysteine which is linked to heart disease, says a new study. People with celiac disease or intolerance to gluten in wheat, are reportedly at increased risk of having high levels of homocysteine.

Because celiac disease is a typical example of a malabsorption syndrome, sufferers are at increased risk of various deficiency states, including folate and vitamin B12, said the researchers. Furthermore, high homocysteine levels are significantly more frequent in newly diagnosed celiac disease patients than healthy controls.

Source: Effect of B vitamin supplementation on plasma homocysteine levels in celiac disease.

Fact #2

“Mom, I don’t want to eat my broccoli.” “Billy, if you don’t eat your broccoli, how do you expect to effectively induce mucosal Phase II enzyme expression in your upper airways.”

Consumption of a naturally occurring compound in broccoli and other cruciferous broccoli sprouts led to a two- to three-fold increase in levels of antioxidant enzymes linked to the protection of human airways against oxidative tissue damage, which leads to inflammation and respiratory conditions like asthma, according to findings from a recent study.

The tissue of cruciferous vegetables, like broccoli, cauliflower, cabbage and Brussels sprouts, contain high levels of the active plant chemicals glucosinolates. These are metabolised by the body into isothiocyanates, which are known to be powerful anti-carcinogens.

The main isothiocyanate from broccoli is sulphoraphane. These compounds can act to protect against respiratory diseases including asthma.

Source: Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway

Fact #3

I love sleep so much that sleep is the first thing I think about when I wake up.

People with a sleep disorder that causes them to kick, cry out or act out during their sleep may be at greater risk of developing dementia or Parkinson’s disease, according to a new study.

REM sleep behavior disorder, as this sleep disorder is called, appears to be a predictor of neurodegenerative disease in more than 50 percent of cases.

“Doctors should pay close attention when following these patients, as their observations could help define the precursors of diseases such as Parkinson’s, Alzheimer’s, Lewy body dementia, or multiple system atrophy,” stated Dr. Montplaisir, principal investigator of the study.

Fact #4

Protecting genes is what I do.
Selenium and vitamin E may offer protection against prostate cancer by changing the expression of certain genes in prostates linked to tumors, says a new study.

Notably, the researchers reported a change in the expression of the TP53 gene, which codes for p53, an important protein involved in the functioning of a normal cell cycle and acting as a tumor suppressor.

“These p53 findings are also consistent with those in proteomic studies of patients’ serum in which combined selenium and vitamin E induced protein expression patterns that were indicative of being free of prostate cancer,” wrote one of the researchers.

Source: Journal of the National Cancer Institute Advance Access originally published online on February 24, 2009

Fact #5

More than one way to keep H. Pylori on the run.

In a new study researchers from Clemson University found various grape extracts and their compounds to be effective at inhibiting Helicobacter pylori, one of the leading causes of gastritis in humans. Following 24 hour treatment, results showed that muscadine grape skin extract had the highest anti-H. pylori effect.

Source: Antibacterial Effects of Grape Extracts on Helicobacter pylori.

Friday February 27, 2009 www.TrueHealthDC.com

Dr. Brady reserves Tuesdays and Thursdays for phone consultations. See TeleHealth. Download intake forms here.

Fact #1

Can I take this in the form of blueberry pie ala mode?

Extracts from blueberries may reduce the size of tumors primarily found in infants and children, and improve survival, suggest new findings from a study with mice.

According to new results from the Ohio State University, mice fed the blueberry extract doubled their lifespan, and had tumors 60 per cent smaller than in control mice.

“This work provides the first evidence demonstrating that blueberry extract can limit tumor formation by inhibiting the formation of blood vessels and inhibiting certain signaling pathways,” said lead author Gayle Gordillo. “Oral administration of blueberry extract represents a potential therapeutic strategy [against] endothelial cell tumors in children.”
Fact #2

If you start itching when your team’s behind with less than two minutes to play, now you know why.

Current research suggests that stress may activate immune cells in your skin, resulting in inflammatory skin disease.

Researchers lead by Dr. Petra Arck of Charité, University of Medicine Berlin and McMaster University in Canada, hypothesized that stress could exacerbate skin disease by increasing the number of immune cells in the skin which in turn are central in initiating and perpetuating skin diseases.

Source: Stress-induced neurogenic inflammation in murine skin skews dendritic cells towards maturation and migration: key role of intercellular adhesion molecule-1/leukocyte function-associated antigen interactions.

Fact #3

You can actually C the improvement!
Increased intake of vitamin C-rich foods may reduce the risk of hardening of the arteries, and ultimately protect against heart disease, says a new study. “Increased intake of vitamin C and fruit and berries seemed to contribute to the lesser progression of the carotid intima media thickness in elderly men who were given dietary advice,” wrote lead author Ingrid Ellingsen.

Source: Vitamin C consumption is associated with less progression in carotid intima media thickness in elderly men: A 3-year intervention study.

Fact #4

Science fiction.

The American Association for Health Freedom (AAHF) has recently criticized a study published by the American Medical Association in the Archives of Internal Medicine (Feb. 9, 2009), which concluded that multivitamin use has little or no influence on the risk of common cancers, cardiovascular disease, or total mortality in postmenopausal women.

“This is very, very weak science, if it can be called science at all, ” said Gretchen DuBeau, executive director of AAHF.

The Alliance for Natural Health has also denounced the research. Dr. Robert Verkerk, executive and scientific director of ANH, said, “We were astonished to find that, with no reasons given, the study specifically excluded multivitamin and mineral supplements that exceeded the US Recommended Daily Allowances, which are known to be far too low to yield useful heart disease and cancer protective effects. Also, any multivitamin with fewer than ten nutrients was excluded from the ‘stress supplements’ group and this would have included some of the highest-dose, limited-combination products that would have been most effective.”
Source: Non Profit Soap Box

Fact #5

Don’t get jealous vitamin C, we still love you.

Vitamin C intake has in the past been associated with a decrease in cold and flu frequency but recent findings have revealed that increased levels of vitamin D may protect against common respiratory infections.

According to findings of a study with about 19,000 adults and adolescents, people with the lowest average levels of vitamin D were about 40 per cent more likely to have a recent respiratory infection, compared to those with higher vitamin D levels.

Source: Association between serum 25-hydroxyvitamin d level and upper respiratory tract infection in the third national health and nutrition examination survey.

Dr. Brady reserves Tuesdays and Thursdays for phone consultations. See TeleHealth

Download intake forms here

Fact #1

How can you possibly get two grams of phytosterols in your diet? Phytosterol-enriched foods are efficacious for reducing levels of LDL cholesterol, with no differences between stanols and sterols, or delivery in fat or non fat foods, says a new review. “For the recommended intake of two grams per day, the expected LDL-C–lowering effect of phytosterols is [about] 9 per cent,” wrote the authors, led by Isabelle Demonty. “A reduction in LDL-C of about 10 per cent would reduce the incidence of cardiovascular disease by about 10-20 per cent.

Source: Continuous dose-response relationship of the LDL-cholesterol-lowering effect of phytosterol intake.

Fact #2

Your local fire department has nothing on this.
Quercetin, the common molecule found in many plant-based foods extinguishes the flames of inflammation before damaging lesions can form in the colon, according to a study. Early lesions in the colon called aberrant crypts, are thought to be a marker or predictor of tumor formation. Quercetin is known to reduce the number of these crypts.

“We did see that both groups, both the control groups and the carcinogen injected groups that were consuming quercetin in their diets, had lower levels of both Cox-1 and Cox-2,” research scientist, Dr. Nancy Turner said. “So that would tend to suggest that there may be opportunity for quercetin to suppress tumor development.”

Source: Quercetin may suppress rat aberrant crypt foci formation by suppressing inflammatory mediators that influence proliferation and apoptosis.

Fact #3

Women and the immune and detox challenge.
According to the latest statistics less than half of women acknowledge their immune system as being their body’s most important defense against preventing illness. And because of their very active and busy lifestyles, one-third of them indicate that being proactive about maintaining their health in general is challenging.

As the concept of detoxification as applied to improving immune health becomes more familiar, as more than three-quarters of women are aware of the term, only four in 10 women look for ways to detoxify their body to improve their overall health.

Fact #4

Maybe the technology that created “The Bionic Woman” was simply this.
According to a recent study low vitamin D levels may actually reduce muscle power and force in adolescent girls. “Our study found that vitamin D is positively related to muscle power, force, velocity and jump height in adolescent girls”, said Kate Ward, PhD, lead researcher on the study.

Source: Vitamin D status and muscle function in post-menarchal adolescent girls.

Fact #5

“And remember kids, if you must drink, don’t drive and if you are pregnant don’t drink.”
Many researchers and clinicians know that binge drinking, even just once, during early pregnancy can cause numerous problems for the fetus, including early postnatal death. But new research on rodent models are findings that dietary zinc supplements throughout pregnancy can reduce some alcohol-related birth defects.

Fetal zinc deficiency may explain some of the birth defects and neurodevelopmental abnormalities associated with alcohol exposure.

Source: Dietary Zinc Supplementation Throughout Pregnancy Protects Against Fetal Dysmorphology and Improves Postnatal Survival After Prenatal Ethanol Exposure in Mice.

If this information helped you, please pass it on to others so they may be helped in the same way.


Dr. Brady Hurst
True Health: Functional Medicine + Chiropractic.
www.TrueHealthDC.com

[CU] is Off

[CU] is Off

[CU] is Off

[CU] is Off

  1. Mom
    March 1, 2009 at 8:20 pm | #1

    Very interesting.

    I do not see how to subscribe.

  2. Amy Jones
    May 22, 2009 at 3:02 pm | #2

    Thanks for the fun facts Dr. Brady. Although some of the jargin lost me, I feel more educated. :) Have a good weekend!

  1. No trackbacks yet.