jump to navigation

How to Prevent Heart Disease with Genetic Testing February 11, 2012

Posted by Dr. Brady Hurst in Heart Health / Cardiovascular Disease.
Tags: , , , ,
3 comments

Go Beyond Cholesterol Testing and Into Genetics

Is Cholesterol Testing A Thing of the Past?

In the past few decades, standard health care had used basic cholesterol testing as the cornerstone for the treatment of heart disease. However, more than 50 percent of those with “normal” values end up hospitalized due to a stroke or heart attack1 .

We now know cholesterol isn’t the sole problem.  What must be considered are genetic factors that influence the behavior of cholesterol. Today we have a advanced heart disease prevention test that tells us our true risk of heart disease.

Cholesterol Size Does Matter

Many studies conclude that cholesterol size and density plays a greater role in the prediction of heart disease than the total amount of cholesterol.

Think of it like this: You have 10 people who want to take a trip. They can either take 1 bus (less traffic) or each take a car. Not only do the cars create more traffic, they can also easily stop on the side of the road (cholesterol sticking to the side of an artery). What’s the size of your cholesterol?

Genetics and Heart Disease

It is true that genetics play a large role in our heart health. Genes determine how efficiently we respond to our environment, however, the key is that our environment ultimately controls our genetics with food being one of the biggest environmental influences.

Yes, this means that your risk of heart disease can weigh heavily on how well you can “genetically digest” food. There is new testing that can help determine what types of food you should eat based on your genetics. Acting on this information will greatly lower your risk of heart disease.

The APO-E Gene

The APO-E gene plays a critical role in how diet influences cholesterol behavior. To keep this simple here is a brief description of the 3 types of APO-E genes and how they respond to diet. Remember, you will fall into a combination of these categories.

APOE2

A person in this category will have the tendency toward lower LDL-Count (“bad” cholesterol even though a misnomer) and higher HDL-Count (“good”), and higher triglycerides, especially in response to dietary simple carbohydrates like grains, sugars, and high glycemic foods. This person will have a reduced risk of heart disease, stroke, and non-alcoholic fatty liver disease.

Lifestyle Changes for APOE2

  • Minimize high-glycemic index foods
  • Cholesterol-lowering effect of a low saturated fat and low-cholesterol diet may be least effective for APOE2 individuals; However, MI risk may be increased with high long-chain saturated fat.
  • Moderate alcohol intake may reduce LDL-C in men (neutral in women) and increase HDL-C.
  • Dietary fiber and exercise help improve the cholesterol size and density tests.
  • Fish oils may reduce triglycerides most effectively in APOE2 individuals.
  • Oral estrogen will increase triglycerides in APOE2 individuals; trans-dermal estrogen replacement therapy may be safer for APOE2 women.

APOE3

  • Only a moderate tendency toward high LDL-count and low HDL-count.
  • Risk is intermediate between APOE2 and APOE4 for heart disease and stroke

Lifestyle Changes for APOE3 Individuals:

  • A low long-chain saturated fat and low cholesterol diet has only a moderate lipid-lowering effect in APOE3 individuals.
  • Dietary fiber, fish oils, and exercise generally improve the cholesterol profile.
  • Alcohol appears to have a neutral effect on LDL-counts.
  • Bio-idential hormone replacement therapy generally improves the lipid profiles, including post-menopausal APOE3 women.

APOE4

  • Tendency toward higher triglycerides and LDL-cholesterol and lower HDL-count.
  • Increased risk of heart disease, stroke, metabolic syndrome, obesity, and toxicity by heavy metals such as lead and mercury

Lifestyle Changes for APOE4 Individuals:

  • Reduce excess weight. Start with a 10 pound goal.
  • A low long-chain saturated fat and low cholesterol diet most effectively lowers LDL-C in APOE4 individuals.
  • Minimize high-glycemic index foods.
  • Minimize alcohol (may raise LDL-C in men and cause damage to the hippocampus (memory center) when homocyctine is high.
  • Fish oils lower triglycerides but may raise LDL-C the most in APOE4 individuals.

The Heart Disease Prevention Test

Unfortunately “basic” is the standard for our current health care system. Even though we have these powerful new heart disease tests, they remain unknown and thus unused by the majority of practitioners.

You do, however, have direct access to this powerful new heart disease blood test.

Provided by our lab, True Health Labs, the new Heart Disease Prevention Test with Genomics can play a critical part when preventing heart disease. If ordered online, one of True Health Labs’s doctors will review the test results with you for free.

Article by Dr. Brady Hurst
Clinic Director for True Health Labs

1American Heart Journal Volume 157, Number 1

Low Vitamin D Levels August 16, 2008

Posted by Dr. Brady Hurst in breast cancer, Candida (yeast) Infections, Hashimoto's Thyroiditis, Hypothyroidism, Lab Testing, thyroid, Vitamin D.
Tags: , , , , , , , , , , , , , , , , ,
4 comments
  • Low Vitamin D levels are very common in the United States because of diminished nutrition in our food supply, the overuse of sunscreen, and the overall lack of outdoor activity in the summer and in winter.
  • AT LEAST 15 minutes (30 minutes for African Americans) of direct sunlight or 30 minutes to 1 hour of shade time is required for adequate Vitamin D production. We have not yet evolved enough to produce more Vitamin D with less sunlight. Our prehistoric ancestors lived near the equator receiving direct UV rays and therefore receiving adequate amounts of Vitamin D…and sadly enough, their food supply was also more nutritious than ours today.
  • Low Vitamin D levels substantially increase the risk of a variety of diseases including several cancers, heart disease, high blood pressure, diabetes, depression, infections (such as Candida), multiple sclerosis, and is linked to an increase of death FROM ALL CAUSES.
  • Low Vitamin D levels in children are linked to a higher risk of death from the H1N1 Swine Flu virus. Have your children’s vitamin d levels tested now.
  • Optimal levels of Vitamin D should read around 50-90 ng/ml. About 90% of my patients show less than 20 ng/ml which is considered an EXTREME DEFICIENCY.
  • Adults and children should be tested once each season. Our office can easily run this test.
  • The majority of us are Vitamin D deficient and should supplement. Vitamin D should be taking in a cod or flax based formula. Vitamin D works best when taken with its co-factors and synergist.
  • I STRESS THAT FULL PERSONAL BALANCE OF ALL VITAMINS, MINERALS, FATTY ACIDS, ENZYMES AND CO-FACTORS ALONG WITH DECREASING THE BURDEN OF HEAVY METALS, VIRAL/BACTERIAL LOADS, AND OXIDATION ARE KEY TO TRULY REGAINING HEALTH.

Our goal here at True Health is to identify the spider web of metabolic dysfunctions that occur in the chronically ill and those of us who are healthy and want to prevent chronic illnesses. We find these dysfunctions through objective laboratory tests. Your personalized plan includes lifestyle, environmental, and dietary changes with an individualized supplement plan.

Because our office has accounts with international laboratories, we are not only able to care for loved ones in-house but now across the world through our unique TeleHealth Service. Finding a good doctor is now made easy.

Dr. Brady Hurst
True Health Center for Advanced Alternative Medicine and Chiropractic.
www.TrueHealthDC.com